Sesame Care vs MangoRx: Which GLP-1 Program Is Better? (2026)

We put Sesame Care and MangoRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend MangoRx

Between these two providers, MangoRx is our pick for most users. It offers a higher overall rating (7.5 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.

MangoRx scores 7.5/10 in our independent evaluation at $195/month, while Sesame Care scores 7.2/10 at $225/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
Sesame Care
$225
MangoRx
$195
Rating
Sesame Care
7.2 / 10
MangoRx
7.5 / 10
Medication Type
Sesame Care
Brand & Compounded
MangoRx
Compounded Only
Insurance Accepted
Sesame Care
Yes
MangoRx
No
States Available
Sesame Care
All 50 states
MangoRx
45 states
Consultation Fee
Sesame Care
$25-75
MangoRx
Free
Shipping
Sesame Care
Paid
MangoRx
Free Shipping
Cancel Anytime
Sesame Care
Yes
MangoRx
Yes
Medical Support
Sesame Care
Licensed physicians booked one visit at a time
MangoRx
Licensed U.S. physicians who stay available for continued support

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

Sesame Care: Detailed Look

Sesame Care

A low-cost telehealth marketplace that matches you with a doctor for as little as $25

7.2/10
Good

Pros

  • About the cheapest consult you'll find, with visits opening at $25
  • Writes scripts for FDA-approved brand-name drugs
  • Clear pay-per-visit pricing and nothing to subscribe to
  • A broad bench of licensed physicians spanning all 50 states

Cons

  • What the drug costs is billed on its own, apart from the visit fee
  • No compounded route here — it's brand-name only, so the drug runs pricier
Best For

Insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately

MangoRx: Detailed Look

MangoRx

A single telehealth service spanning weight loss, men's health, and broader wellness needs

7.5/10
Good

Pros

  • Handles more than weight loss — ED, hair loss, and skincare too
  • Every prescription is written by a licensed U.S. physician
  • Shipping is free on whatever you order
  • An easy online intake that skips the need for an appointment

Cons

  • You won't see the full pricing until you finish the intake form
  • Stocks compounded formulas only, with no brand-name versions
Best For

People who want one telehealth account that spans weight loss and men's health

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with MangoRx at $195/month. A ballpark opening figure for the GLP-1 program.

You want the highest-rated program

MangoRx has the edge with a 7.5 rating.

You have insurance coverage

Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.

You want affordable compounded options

MangoRx focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: Sesame Care offers licensed physicians booked one visit at a time, while MangoRx provides licensed u.s. physicians who stay available for continued support.

You are willing to invest more for premium care

Sesame Care at $225/month may offer features that justify the premium.

Sesame Care

Starting at $225/mo · Good

Visit Sesame Care

MangoRx

Starting at $195/mo · Good

Visit MangoRx

Frequently Asked Questions

Is Sesame Care better than MangoRx?

Sesame Care has a 7.2 rating while MangoRx has a 7.5 rating. The better choice depends on your priorities — Sesame Care is best for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately, while MangoRx is best for people who want one telehealth account that spans weight loss and men's health.

How much does Sesame Care cost compared to MangoRx?

Sesame Care starts at $225/month (visits run $25-75, and the medication is billed separately at pharmacy rates ($200-1,400/mo). with insurance savings cards the total opens around $225/mo. the drug is not part of the visit fee.), while MangoRx starts at $195/month (a ballpark opening figure for the glp-1 program).

Do Sesame Care and MangoRx accept insurance?

Sesame Care accepts insurance. MangoRx does not accept insurance.

Which GLP-1 medications does Sesame Care offer vs MangoRx?

Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus. MangoRx offers Compounded Semaglutide, Compounded Tirzepatide.

Can I cancel Sesame Care or MangoRx at any time?

Sesame Care allows cancel anytime. MangoRx also allows cancel anytime.

Are Sesame Care and MangoRx available in my state?

Sesame Care is available in all 50 states. MangoRx is available in 45 states.

Not sure Sesame Care or MangoRx is right for you?

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