Ro vs Enhance MD: Which GLP-1 Program Is Better? (2026)
We put Ro and Enhance MD head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 6.7), both brand-name and compounded medication options. That said, Ro may be the better fit if you are looking for insured patients who want brand-name drugs from a well-established platform.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Ro scores 6.7/10 at $99/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Ro | Enhance MD |
|---|---|---|
| Monthly Price | $99 | $249 |
| Rating | 6.7 / 10 | 8.3 / 10 |
| Medication Type | Brand-Name Only | Brand & Compounded |
| Insurance Accepted | Yes | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included in membership | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified doctors, coaching, and around-the-clock messaging | Board-certified doctors |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Ro: Detailed Look
Ro
The biggest name in telehealth, now running GLP-1 programs
Pros
- The largest telehealth name, relied on by millions of patients
- Sticks exclusively to FDA-approved brand-name drugs
- Takes insurance, which can cut your out-of-pocket cost sharply
- Its full Body Program folds in coaching and round-the-clock messaging
Cons
- The drug is billed on top of the $99/month program fee
- Without insurance, the total can run pricey
Insured patients who want brand-name drugs from a well-established platform
Enhance MD: Detailed Look
Enhance MD
Doctor-directed weight management that also offers NAD+ add-ons
Pros
- Wallet-friendly way in, with pricing that begins at $115/month
- An uncommon NAD+ therapy choice to pair with your GLP-1
- Every protocol is overseen by board-certified doctors
Cons
- Claims that NAD+ aids weight loss aren't well supported by trials
- It's hazy about which drugs are compounded versus brand-name
Cost-minded patients curious about stacking combination therapies
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Ro at $99/month. Covers Body Program membership only; the drug itself is billed separately.
Enhance MD has the edge with a 8.3 rating.
Ro accepts insurance, which can significantly reduce your out-of-pocket cost.
Choose Ro which exclusively prescribes brand-name medications.
Compare their support: Ro offers board-certified doctors, coaching, and around-the-clock messaging, while Enhance MD provides board-certified doctors.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Ro better than Enhance MD?
Ro has a 6.7 rating while Enhance MD has a 8.3 rating. The better choice depends on your priorities — Ro is best for insured patients who want brand-name drugs from a well-established platform, while Enhance MD is best for cost-minded patients curious about stacking combination therapies.
How much does Ro cost compared to Enhance MD?
Ro starts at $99/month (covers body program membership only; the drug itself is billed separately), while Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%).
Do Ro and Enhance MD accept insurance?
Ro accepts insurance. Enhance MD does not accept insurance.
Which GLP-1 medications does Ro offer vs Enhance MD?
Ro offers Wegovy, Zepbound, Ozempic. Enhance MD offers Semaglutide, Tirzepatide, NAD+.
Can I cancel Ro or Enhance MD at any time?
Ro allows cancel anytime. Enhance MD also allows cancel anytime.
Are Ro and Enhance MD available in my state?
Ro is available in all 50 states. Enhance MD is available in all 50 states.
Not sure Ro or Enhance MD is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.