Oak Longevity vs Enhance MD: Which GLP-1 Program Is Better? (2026)

We put Oak Longevity and Enhance MD head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Oak Longevity

Between these two providers, Oak Longevity is our pick for most users. It offers a higher overall rating (9 vs 8.3), more affordable pricing. That said, Enhance MD may be the better fit if you are looking for cost-minded patients curious about stacking combination therapies.

Oak Longevity scores 9/10 in our independent evaluation at $130/month, while Enhance MD scores 8.3/10 at $249/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
Oak Longevity
$130
Enhance MD
$249
Rating
Oak Longevity
9 / 10
Enhance MD
8.3 / 10
Medication Type
Oak Longevity
Compounded Only
Enhance MD
Brand & Compounded
Insurance Accepted
Oak Longevity
No
Enhance MD
No
States Available
Oak Longevity
All 50 states
Enhance MD
All 50 states
Consultation Fee
Oak Longevity
Included
Enhance MD
Included
Shipping
Oak Longevity
Free Shipping
Enhance MD
Free Shipping
Cancel Anytime
Oak Longevity
Yes
Enhance MD
Yes
Medical Support
Oak Longevity
Board-certified doctors, complimentary coaching, and a quick-to-respond care team
Enhance MD
Board-certified doctors

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

Oak Longevity: Detailed Look

Oak Longevity

Low-cost GLP-1 starting at $130/mo — semaglutide and tirzepatide, free delivery and coaching included

9/10
Excellent

Pros

  • Sits near the bottom on price: semaglutide from $130/mo, tirzepatide from $199/mo
  • Delivery and health coaching both come at no extra charge
  • Pay month by month with no subscription locks or membership dues
  • Approvals land the same day, with 10,000+ happy patients so far

Cons

  • Stocks compounded formulas only, with no brand drugs offered
  • A recent entrant, so outside reviews remain scarce
Best For

Cost-minded shoppers chasing rock-bottom pricing with coaching and zero membership dues

Enhance MD: Detailed Look

Enhance MD

Doctor-directed weight management that also offers NAD+ add-ons

8.3/10
Good

Pros

  • Wallet-friendly way in, with pricing that begins at $115/month
  • An uncommon NAD+ therapy choice to pair with your GLP-1
  • Every protocol is overseen by board-certified doctors

Cons

  • Claims that NAD+ aids weight loss aren't well supported by trials
  • It's hazy about which drugs are compounded versus brand-name
Best For

Cost-minded patients curious about stacking combination therapies

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with Oak Longevity at $130/month. Semaglutide at $130/mo and tirzepatide at $199/mo, with every dose priced the same. Apply code OAKNEW50 to take $50 off your first month..

You want the highest-rated program

Oak Longevity has the edge with a 9 rating.

You want affordable compounded options

Oak Longevity focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: Oak Longevity offers board-certified doctors, complimentary coaching, and a quick-to-respond care team, while Enhance MD provides board-certified doctors.

You are willing to invest more for premium care

Enhance MD at $249/month may offer features that justify the premium.

Oak Longevity

Starting at $130/mo · Excellent

Visit Oak Longevity

Enhance MD

Starting at $249/mo · Good

Visit Enhance MD

Frequently Asked Questions

Is Oak Longevity better than Enhance MD?

Oak Longevity has a 9 rating while Enhance MD has a 8.3 rating. The better choice depends on your priorities — Oak Longevity is best for cost-minded shoppers chasing rock-bottom pricing with coaching and zero membership dues, while Enhance MD is best for cost-minded patients curious about stacking combination therapies.

How much does Oak Longevity cost compared to Enhance MD?

Oak Longevity starts at $130/month (semaglutide at $130/mo and tirzepatide at $199/mo, with every dose priced the same. apply code oaknew50 to take $50 off your first month.), while Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%).

Do Oak Longevity and Enhance MD accept insurance?

Oak Longevity does not accept insurance. Enhance MD does not accept insurance.

Which GLP-1 medications does Oak Longevity offer vs Enhance MD?

Oak Longevity offers Compounded Semaglutide, Compounded Tirzepatide. Enhance MD offers Semaglutide, Tirzepatide, NAD+.

Can I cancel Oak Longevity or Enhance MD at any time?

Oak Longevity allows cancel anytime. Enhance MD also allows cancel anytime.

Are Oak Longevity and Enhance MD available in my state?

Oak Longevity is available in all 50 states. Enhance MD is available in all 50 states.

Not sure Oak Longevity or Enhance MD is right for you?

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