Novi vs SynergyRx: Which GLP-1 Program Is Better? (2026)
We put Novi and SynergyRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Novi
Between these two providers, Novi is our pick for most users. It offers a higher overall rating (7.3 vs 5.6), more affordable pricing. That said, SynergyRx may be the better fit if you are looking for people who want one predictable bundled price and support they can reach at any hour.
Novi scores 7.3/10 in our independent evaluation at $199/month, while SynergyRx scores 5.6/10 at $200/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Novi | SynergyRx |
|---|---|---|
| Monthly Price | $199 | $200 |
| Rating | 7.3 / 10 | 5.6 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | 45 states | 45 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians you can reach without limits, plus nutritionist-designed meal plans | Licensed providers reachable by message any hour, with no limit on check-ins |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Novi: Detailed Look
Novi
Commitment-free GLP-1 care that pairs $199/mo pricing with as much clinician time as you need
Pros
- Clear bundled pricing where nothing extra gets tacked on later
- Reach a clinician as often as you like for check-ins and dose tweaks
- Pay month by month, free of contracts or any minimum stay
- Comes with meal plans put together by a nutritionist plus an online community
Cons
- Once your prescription ships, that order can't be refunded
- A fairly young service that hasn't built up a long history yet
People who want GLP-1 care they can leave anytime, backed by plenty of clinician support
SynergyRx: Detailed Look
SynergyRx
All-in-one GLP-1 plans that bundle round-the-clock support and skip surprise charges
Pros
- One bundled rate covers it all, with no charge for messaging or dose changes
- Every order ships expedited at no extra cost
- Reach support at any hour and message as much as you want
- Works with several certified pharmacies to keep supply steady
Cons
- At $200/mo, the entry price is middle-of-the-pack for compounded semaglutide
- Coverage doesn't stretch to every state
People who want one predictable bundled price and support they can reach at any hour
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Novi at $199/month. Opens at $199 for the first month, with nothing locking you into a contract.
Novi has the edge with a 7.3 rating.
Compare their support: Novi offers licensed physicians you can reach without limits, plus nutritionist-designed meal plans, while SynergyRx provides licensed providers reachable by message any hour, with no limit on check-ins.
SynergyRx at $200/month may offer features that justify the premium.
Frequently Asked Questions
Is Novi better than SynergyRx?
Novi has a 7.3 rating while SynergyRx has a 5.6 rating. The better choice depends on your priorities — Novi is best for people who want glp-1 care they can leave anytime, backed by plenty of clinician support, while SynergyRx is best for people who want one predictable bundled price and support they can reach at any hour.
How much does Novi cost compared to SynergyRx?
Novi starts at $199/month (opens at $199 for the first month, with nothing locking you into a contract), while SynergyRx starts at $200/month (semaglutide comes in at $200/mo, with tirzepatide ranging from $299 to $347/mo).
Do Novi and SynergyRx accept insurance?
Novi does not accept insurance. SynergyRx does not accept insurance.
Which GLP-1 medications does Novi offer vs SynergyRx?
Novi offers Compounded Semaglutide, Brand-name GLP-1s. SynergyRx offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro.
Can I cancel Novi or SynergyRx at any time?
Novi allows cancel anytime. SynergyRx also allows cancel anytime.
Are Novi and SynergyRx available in my state?
Novi is available in 45 states. SynergyRx is available in 45 states.
Not sure Novi or SynergyRx is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.