MyStart Health vs Yucca Health: Which GLP-1 Program Is Better? (2026)

We put MyStart Health and Yucca Health head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Yucca Health

Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 8.5), more affordable pricing. That said, MyStart Health may be the better fit if you are looking for people who value a money-back results pledge alongside a frozen price.

Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while MyStart Health scores 8.5/10 at $224/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
MyStart Health
$224
Yucca Health
$146
Rating
MyStart Health
8.5 / 10
Yucca Health
9.2 / 10
Medication Type
MyStart Health
Brand & Compounded
Yucca Health
Compounded Only
Insurance Accepted
MyStart Health
No
Yucca Health
No
States Available
MyStart Health
All 50 states
Yucca Health
All 50 states
Consultation Fee
MyStart Health
Free
Yucca Health
Free
Shipping
MyStart Health
Free Shipping
Yucca Health
Free Shipping
Cancel Anytime
MyStart Health
Yes
Yucca Health
No
Medical Support
MyStart Health
U.S.-licensed doctors you can reach without any cap on clinician visits
Yucca Health
U.S.-licensed doctors (Dr. Wasef, Dr. Sakla) guiding your care with reviews inside 24 hours

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

MyStart Health: Detailed Look

MyStart Health

GLP-1 plans backed by a locked-in price and a results-or-refund pledge

8.5/10
Excellent

Pros

  • A locked rate means stepping up your dose never bumps the price
  • Drop 10% of your body weight inside four months or get your money back
  • One bundled price folds in free shipping and lab work
  • Reaches all 50 states and turns consultations around within a day

Cons

  • A handful of customers mention delays getting orders shipped out
  • Switching to tirzepatide costs a lot more at $429 a month
Best For

People who value a money-back results pledge alongside a frozen price

Yucca Health: Detailed Look

Yucca Health

A LegitScript-verified GLP-1 service with doctors you can name and pay-over-time options

9.2/10
Excellent

Pros

  • Both the pharmacy and telehealth side carry LegitScript verification
  • More than 1,000 verified patient reviews put it at 4.6 out of 5 on Trustpilot
  • You'll know your doctors by name: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
  • Spread the cost over time through Klarna, Affirm, or Afterpay

Cons

  • Locking in the lowest price means signing on for six months
  • Everything's compounded here — no brand-name versions offered
Best For

People wanting a LegitScript-verified provider with real patient reviews and pay-over-time options

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with Yucca Health at $146/month. Six-month semaglutide plan at $146/mo, tirzepatide $258/mo. Pay via Klarna, Affirm, or Afterpay..

You want the highest-rated program

Yucca Health has the edge with a 9.2 rating.

You want affordable compounded options

Yucca Health focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: MyStart Health offers u.s.-licensed doctors you can reach without any cap on clinician visits, while Yucca Health provides u.s.-licensed doctors (dr. wasef, dr. sakla) guiding your care with reviews inside 24 hours.

You are willing to invest more for premium care

MyStart Health at $224/month may offer features that justify the premium.

MyStart Health

Starting at $224/mo · Excellent

Visit MyStart Health

Yucca Health

Starting at $146/mo · Excellent

Visit Yucca Health

Frequently Asked Questions

Is MyStart Health better than Yucca Health?

MyStart Health has a 8.5 rating while Yucca Health has a 9.2 rating. The better choice depends on your priorities — MyStart Health is best for people who value a money-back results pledge alongside a frozen price, while Yucca Health is best for people wanting a legitscript-verified provider with real patient reviews and pay-over-time options.

How much does MyStart Health cost compared to Yucca Health?

MyStart Health starts at $224/month (normally $299/mo; code selflove25 trims 25% off to $224/mo. meds, labs, shipping, and unlimited clinician access all included), while Yucca Health starts at $146/month (six-month semaglutide plan at $146/mo, tirzepatide $258/mo. pay via klarna, affirm, or afterpay.).

Do MyStart Health and Yucca Health accept insurance?

MyStart Health does not accept insurance. Yucca Health does not accept insurance.

Which GLP-1 medications does MyStart Health offer vs Yucca Health?

MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy. Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.

Can I cancel MyStart Health or Yucca Health at any time?

MyStart Health allows cancel anytime. Yucca Health may have cancellation restrictions.

Are MyStart Health and Yucca Health available in my state?

MyStart Health is available in all 50 states. Yucca Health is available in all 50 states.

Not sure MyStart Health or Yucca Health is right for you?

Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.

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