MyStart Health vs TMates: Which GLP-1 Program Is Better? (2026)
We put MyStart Health and TMates head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend MyStart Health
Between these two providers, MyStart Health is our pick for most users. It offers a higher overall rating (8.5 vs 7.8), availability in all 50 states, both brand-name and compounded medication options. That said, TMates may be the better fit if you are looking for insured patients who want a coached glp-1 program with a few medication choices.
MyStart Health scores 8.5/10 in our independent evaluation at $224/month, while TMates scores 7.8/10 at $199/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | MyStart Health | TMates |
|---|---|---|
| Monthly Price | $224 | $199 |
| Rating | 8.5 / 10 | 7.8 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | 45 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | U.S.-licensed doctors you can reach without any cap on clinician visits | Licensed clinicians paired with text-message coaching and digital check-ins |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
MyStart Health: Detailed Look
MyStart Health
GLP-1 plans backed by a locked-in price and a results-or-refund pledge
Pros
- A locked rate means stepping up your dose never bumps the price
- Drop 10% of your body weight inside four months or get your money back
- One bundled price folds in free shipping and lab work
- Reaches all 50 states and turns consultations around within a day
Cons
- A handful of customers mention delays getting orders shipped out
- Switching to tirzepatide costs a lot more at $429 a month
People who value a money-back results pledge alongside a frozen price
TMates: Detailed Look
TMates
A GLP-1 weight loss program you can put through most major insurance plans
Pros
- Among the rare GLP-1 services that will actually take major insurance
- A single flat rate wraps in meds, visits, coaching, and delivery
- Text-based coaching and digital check-ins run around the clock
- Phentermine is available for those who aren't GLP-1 candidates
Cons
- It's a younger platform, so independent reviews remain sparse
- You'll need to enroll before the full program details are confirmed
Insured patients who want a coached GLP-1 program with a few medication choices
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with TMates at $199/month. Semaglutide at $199/mo, tirzepatide at $297/mo.
MyStart Health has the edge with a 8.5 rating.
TMates accepts insurance, which can significantly reduce your out-of-pocket cost.
TMates focuses on compounded medications at a lower price point.
Compare their support: MyStart Health offers u.s.-licensed doctors you can reach without any cap on clinician visits, while TMates provides licensed clinicians paired with text-message coaching and digital check-ins.
MyStart Health at $224/month may offer features that justify the premium.
Frequently Asked Questions
Is MyStart Health better than TMates?
MyStart Health has a 8.5 rating while TMates has a 7.8 rating. The better choice depends on your priorities — MyStart Health is best for people who value a money-back results pledge alongside a frozen price, while TMates is best for insured patients who want a coached glp-1 program with a few medication choices.
How much does MyStart Health cost compared to TMates?
MyStart Health starts at $224/month (normally $299/mo; code selflove25 trims 25% off to $224/mo. meds, labs, shipping, and unlimited clinician access all included), while TMates starts at $199/month (semaglutide at $199/mo, tirzepatide at $297/mo).
Do MyStart Health and TMates accept insurance?
MyStart Health does not accept insurance. TMates accepts insurance.
Which GLP-1 medications does MyStart Health offer vs TMates?
MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy. TMates offers Compounded Semaglutide, Compounded Tirzepatide, Phentermine.
Can I cancel MyStart Health or TMates at any time?
MyStart Health allows cancel anytime. TMates also allows cancel anytime.
Are MyStart Health and TMates available in my state?
MyStart Health is available in all 50 states. TMates is available in 45 states.
Not sure MyStart Health or TMates is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.