MyStart Health vs SynergyRx: Which GLP-1 Program Is Better? (2026)
We put MyStart Health and SynergyRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend MyStart Health
Between these two providers, MyStart Health is our pick for most users. It offers a higher overall rating (8.5 vs 5.6), availability in all 50 states. That said, SynergyRx may be the better fit if you are looking for people who want one predictable bundled price and support they can reach at any hour.
MyStart Health scores 8.5/10 in our independent evaluation at $224/month, while SynergyRx scores 5.6/10 at $200/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | MyStart Health | SynergyRx |
|---|---|---|
| Monthly Price | $224 | $200 |
| Rating | 8.5 / 10 | 5.6 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | 45 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | U.S.-licensed doctors you can reach without any cap on clinician visits | Licensed providers reachable by message any hour, with no limit on check-ins |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
MyStart Health: Detailed Look
MyStart Health
GLP-1 plans backed by a locked-in price and a results-or-refund pledge
Pros
- A locked rate means stepping up your dose never bumps the price
- Drop 10% of your body weight inside four months or get your money back
- One bundled price folds in free shipping and lab work
- Reaches all 50 states and turns consultations around within a day
Cons
- A handful of customers mention delays getting orders shipped out
- Switching to tirzepatide costs a lot more at $429 a month
People who value a money-back results pledge alongside a frozen price
SynergyRx: Detailed Look
SynergyRx
All-in-one GLP-1 plans that bundle round-the-clock support and skip surprise charges
Pros
- One bundled rate covers it all, with no charge for messaging or dose changes
- Every order ships expedited at no extra cost
- Reach support at any hour and message as much as you want
- Works with several certified pharmacies to keep supply steady
Cons
- At $200/mo, the entry price is middle-of-the-pack for compounded semaglutide
- Coverage doesn't stretch to every state
People who want one predictable bundled price and support they can reach at any hour
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with SynergyRx at $200/month. Semaglutide comes in at $200/mo, with tirzepatide ranging from $299 to $347/mo.
MyStart Health has the edge with a 8.5 rating.
Compare their support: MyStart Health offers u.s.-licensed doctors you can reach without any cap on clinician visits, while SynergyRx provides licensed providers reachable by message any hour, with no limit on check-ins.
MyStart Health at $224/month may offer features that justify the premium.
Frequently Asked Questions
Is MyStart Health better than SynergyRx?
MyStart Health has a 8.5 rating while SynergyRx has a 5.6 rating. The better choice depends on your priorities — MyStart Health is best for people who value a money-back results pledge alongside a frozen price, while SynergyRx is best for people who want one predictable bundled price and support they can reach at any hour.
How much does MyStart Health cost compared to SynergyRx?
MyStart Health starts at $224/month (normally $299/mo; code selflove25 trims 25% off to $224/mo. meds, labs, shipping, and unlimited clinician access all included), while SynergyRx starts at $200/month (semaglutide comes in at $200/mo, with tirzepatide ranging from $299 to $347/mo).
Do MyStart Health and SynergyRx accept insurance?
MyStart Health does not accept insurance. SynergyRx does not accept insurance.
Which GLP-1 medications does MyStart Health offer vs SynergyRx?
MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy. SynergyRx offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro.
Can I cancel MyStart Health or SynergyRx at any time?
MyStart Health allows cancel anytime. SynergyRx also allows cancel anytime.
Are MyStart Health and SynergyRx available in my state?
MyStart Health is available in all 50 states. SynergyRx is available in 45 states.
Not sure MyStart Health or SynergyRx is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.