MyStart Health vs SkinnyRx: Which GLP-1 Program Is Better? (2026)
We put MyStart Health and SkinnyRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend SkinnyRx
Between these two providers, SkinnyRx is our pick for most users. It offers a higher overall rating (9.1 vs 8.5), more affordable pricing. That said, MyStart Health may be the better fit if you are looking for people who value a money-back results pledge alongside a frozen price.
SkinnyRx scores 9.1/10 in our independent evaluation at $199/month, while MyStart Health scores 8.5/10 at $224/month. Both programs connect you with a licensed physician and deliver medication straight to your door. SkinnyRx also offers oral GLP-1 options for patients who prefer pills over injections. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | MyStart Health | SkinnyRx |
|---|---|---|
| Monthly Price | $224 | $199 |
| Rating | 8.5 / 10 | 9.1 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 48 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | U.S.-licensed doctors you can reach without any cap on clinician visits | U.S.-licensed doctors who turn around prescription reviews in 24-48 hours |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
MyStart Health: Detailed Look
MyStart Health
GLP-1 plans backed by a locked-in price and a results-or-refund pledge
Pros
- A locked rate means stepping up your dose never bumps the price
- Drop 10% of your body weight inside four months or get your money back
- One bundled price folds in free shipping and lab work
- Reaches all 50 states and turns consultations around within a day
Cons
- A handful of customers mention delays getting orders shipped out
- Switching to tirzepatide costs a lot more at $429 a month
People who value a money-back results pledge alongside a frozen price
SkinnyRx: Detailed Look
SkinnyRx
A rapidly scaling GLP-1 service offering pills, sublinguals, and shots with Affirm financing
Pros
- Take it three ways — as a shot, under the tongue, or as a tablet
- Overnight delivery is free and ships from FDA-regulated U.S. pharmacies
- Billed month to month, so you're never locked into a contract
- Thousands of verified Trustpilot reviews average a 4.8 out of 5
Cons
- You'll pay cash — they don't run anything through insurance
- Only compounded formulas here; brand-name versions aren't offered
People who want their GLP-1 in several formats — tablet, sublingual, or injection
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with SkinnyRx at $199/month. Semaglutide runs $199/mo; tirzepatide climbs as high as $349/mo.
SkinnyRx has the edge with a 9.1 rating.
SkinnyRx focuses on compounded medications at a lower price point.
Compare their support: MyStart Health offers u.s.-licensed doctors you can reach without any cap on clinician visits, while SkinnyRx provides u.s.-licensed doctors who turn around prescription reviews in 24-48 hours.
MyStart Health at $224/month may offer features that justify the premium.
Frequently Asked Questions
Is MyStart Health better than SkinnyRx?
MyStart Health has a 8.5 rating while SkinnyRx has a 9.1 rating. The better choice depends on your priorities — MyStart Health is best for people who value a money-back results pledge alongside a frozen price, while SkinnyRx is best for people who want their glp-1 in several formats — tablet, sublingual, or injection.
How much does MyStart Health cost compared to SkinnyRx?
MyStart Health starts at $224/month (normally $299/mo; code selflove25 trims 25% off to $224/mo. meds, labs, shipping, and unlimited clinician access all included), while SkinnyRx starts at $199/month (semaglutide runs $199/mo; tirzepatide climbs as high as $349/mo).
Do MyStart Health and SkinnyRx accept insurance?
MyStart Health does not accept insurance. SkinnyRx does not accept insurance.
Which GLP-1 medications does MyStart Health offer vs SkinnyRx?
MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy. SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets).
Can I cancel MyStart Health or SkinnyRx at any time?
MyStart Health allows cancel anytime. SkinnyRx also allows cancel anytime.
Are MyStart Health and SkinnyRx available in my state?
MyStart Health is available in all 50 states. SkinnyRx is available in 48 states.
Not sure MyStart Health or SkinnyRx is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.