MangoRx vs Trimi: Which GLP-1 Program Is Better? (2026)
We put MangoRx and Trimi head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Trimi
Between these two providers, Trimi is our pick for most users. It offers a higher overall rating (8.1 vs 7.5), more affordable pricing, availability in all 50 states. That said, MangoRx may be the better fit if you are looking for people who want one telehealth account that spans weight loss and men's health.
Trimi scores 8.1/10 in our independent evaluation at $99/month, while MangoRx scores 7.5/10 at $195/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | MangoRx | Trimi |
|---|---|---|
| Monthly Price | $195 | $99 |
| Rating | 7.5 / 10 | 8.1 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | No |
| States Available | 45 states | All 50 states |
| Consultation Fee | Free | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed U.S. physicians who stay available for continued support | US-licensed clinicians via Arora Health |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
MangoRx: Detailed Look
MangoRx
A single telehealth service spanning weight loss, men's health, and broader wellness needs
Pros
- Handles more than weight loss — ED, hair loss, and skincare too
- Every prescription is written by a licensed U.S. physician
- Shipping is free on whatever you order
- An easy online intake that skips the need for an appointment
Cons
- You won't see the full pricing until you finish the intake form
- Stocks compounded formulas only, with no brand-name versions
People who want one telehealth account that spans weight loss and men's health
Trimi: Detailed Look
Trimi
Flat-price compounded GLP-1 — your cost stays the same as your dose climbs
Pros
- Flat monthly price that doesn't change as your dose is adjusted
- Compounded semaglutide from $99/mo, tirzepatide from $125/mo
- US-licensed clinicians (via Arora Health) prescribing in all 50 states
- 100% online with medication shipped to your door
Cons
- The lowest $99/$125 pricing requires an annual plan
- Compounded medications are not FDA-approved
Self-pay patients who want a flat, predictable price as their dose increases
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Trimi at $99/month. Compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases..
Trimi has the edge with a 8.1 rating.
Compare their support: MangoRx offers licensed u.s. physicians who stay available for continued support, while Trimi provides us-licensed clinicians via arora health.
MangoRx at $195/month may offer features that justify the premium.
Frequently Asked Questions
Is MangoRx better than Trimi?
MangoRx has a 7.5 rating while Trimi has a 8.1 rating. The better choice depends on your priorities — MangoRx is best for people who want one telehealth account that spans weight loss and men's health, while Trimi is best for self-pay patients who want a flat, predictable price as their dose increases.
How much does MangoRx cost compared to Trimi?
MangoRx starts at $195/month (a ballpark opening figure for the glp-1 program), while Trimi starts at $99/month (compounded semaglutide $99/mo and tirzepatide $125/mo on annual plans — and the price doesn't rise as your dose increases.).
Do MangoRx and Trimi accept insurance?
MangoRx does not accept insurance. Trimi does not accept insurance.
Which GLP-1 medications does MangoRx offer vs Trimi?
MangoRx offers Compounded Semaglutide, Compounded Tirzepatide. Trimi offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel MangoRx or Trimi at any time?
MangoRx allows cancel anytime. Trimi also allows cancel anytime.
Are MangoRx and Trimi available in my state?
MangoRx is available in 45 states. Trimi is available in all 50 states.
Not sure MangoRx or Trimi is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.