Hone Health vs Yucca Health: Which GLP-1 Program Is Better? (2026)

We put Hone Health and Yucca Health head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Yucca Health

Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 6.3), more affordable pricing, availability in all 50 states. That said, Hone Health may be the better fit if you are looking for people wanting one platform that handles weight loss alongside hormones and labs.

Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while Hone Health scores 6.3/10 at $160/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
Hone Health
$160
Yucca Health
$146
Rating
Hone Health
6.3 / 10
Yucca Health
9.2 / 10
Medication Type
Hone Health
Compounded Only
Yucca Health
Compounded Only
Insurance Accepted
Hone Health
No
Yucca Health
No
States Available
Hone Health
44 states
Yucca Health
All 50 states
Consultation Fee
Hone Health
$65 initial lab kit
Yucca Health
Free
Shipping
Hone Health
Free Shipping
Yucca Health
Free Shipping
Cancel Anytime
Hone Health
Yes
Yucca Health
No
Medical Support
Hone Health
Licensed doctors who pair lab testing with continued monitoring
Yucca Health
U.S.-licensed doctors (Dr. Wasef, Dr. Sakla) guiding your care with reviews inside 24 hours

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

Hone Health: Detailed Look

Hone Health

Soup-to-nuts telehealth spanning GLP-1s, hormone therapy, and bloodwork

6.3/10
Fair

Pros

  • One platform handling weight loss, hormones, longevity, and lab work
  • In-depth diagnostics come baked in to steer your treatment
  • Confidential video visits run by licensed doctors
  • Your prescriptions arrive shipped straight to your address

Cons

  • There's a standalone membership charge ($25-149/mo) layered over the meds
  • Semaglutide isn't stocked — your choices are liraglutide or tirzepatide
Best For

People wanting one platform that handles weight loss alongside hormones and labs

Yucca Health: Detailed Look

Yucca Health

A LegitScript-verified GLP-1 service with doctors you can name and pay-over-time options

9.2/10
Excellent

Pros

  • Both the pharmacy and telehealth side carry LegitScript verification
  • More than 1,000 verified patient reviews put it at 4.6 out of 5 on Trustpilot
  • You'll know your doctors by name: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
  • Spread the cost over time through Klarna, Affirm, or Afterpay

Cons

  • Locking in the lowest price means signing on for six months
  • Everything's compounded here — no brand-name versions offered
Best For

People wanting a LegitScript-verified provider with real patient reviews and pay-over-time options

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with Yucca Health at $146/month. Six-month semaglutide plan at $146/mo, tirzepatide $258/mo. Pay via Klarna, Affirm, or Afterpay..

You want the highest-rated program

Yucca Health has the edge with a 9.2 rating.

You want comprehensive medical support

Compare their support: Hone Health offers licensed doctors who pair lab testing with continued monitoring, while Yucca Health provides u.s.-licensed doctors (dr. wasef, dr. sakla) guiding your care with reviews inside 24 hours.

You are willing to invest more for premium care

Hone Health at $160/month may offer features that justify the premium.

Hone Health

Starting at $160/mo · Fair

Visit Hone Health

Yucca Health

Starting at $146/mo · Excellent

Visit Yucca Health

Frequently Asked Questions

Is Hone Health better than Yucca Health?

Hone Health has a 6.3 rating while Yucca Health has a 9.2 rating. The better choice depends on your priorities — Hone Health is best for people wanting one platform that handles weight loss alongside hormones and labs, while Yucca Health is best for people wanting a legitscript-verified provider with real patient reviews and pay-over-time options.

How much does Hone Health cost compared to Yucca Health?

Hone Health starts at $160/month (liraglutide at $160/mo, tirzepatide $349-499/mo, plus a membership fee on top), while Yucca Health starts at $146/month (six-month semaglutide plan at $146/mo, tirzepatide $258/mo. pay via klarna, affirm, or afterpay.).

Do Hone Health and Yucca Health accept insurance?

Hone Health does not accept insurance. Yucca Health does not accept insurance.

Which GLP-1 medications does Hone Health offer vs Yucca Health?

Hone Health offers Compounded Liraglutide, Compounded Tirzepatide. Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.

Can I cancel Hone Health or Yucca Health at any time?

Hone Health allows cancel anytime. Yucca Health may have cancellation restrictions.

Are Hone Health and Yucca Health available in my state?

Hone Health is available in 44 states. Yucca Health is available in all 50 states.

Not sure Hone Health or Yucca Health is right for you?

Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.

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