Enhance MD vs Zealthy: Which GLP-1 Program Is Better? (2026)

We put Enhance MD and Zealthy head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.

Julian Caraulani
Julian Caraulani
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Enhance MD

Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 7). That said, Zealthy may be the better fit if you are looking for people who want the flexibility to move between compounded and brand-name glp-1s.

Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Zealthy scores 7/10 at $151/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.

Side-by-Side Comparison

Monthly Price
Enhance MD
$249
Zealthy
$151
Rating
Enhance MD
8.3 / 10
Zealthy
7 / 10
Medication Type
Enhance MD
Brand & Compounded
Zealthy
Brand & Compounded
Insurance Accepted
Enhance MD
No
Zealthy
No
States Available
Enhance MD
All 50 states
Zealthy
All 50 states
Consultation Fee
Enhance MD
Included
Zealthy
$135/mo membership
Shipping
Enhance MD
Free Shipping
Zealthy
Free Shipping
Cancel Anytime
Enhance MD
Yes
Zealthy
Yes
Medical Support
Enhance MD
Board-certified doctors
Zealthy
Licensed physicians who provide continued clinical support

Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.

Enhance MD: Detailed Look

Enhance MD

Doctor-directed weight management that also offers NAD+ add-ons

8.3/10
Good

Pros

  • Wallet-friendly way in, with pricing that begins at $115/month
  • An uncommon NAD+ therapy choice to pair with your GLP-1
  • Every protocol is overseen by board-certified doctors

Cons

  • Claims that NAD+ aids weight loss aren't well supported by trials
  • It's hazy about which drugs are compounded versus brand-name
Best For

Cost-minded patients curious about stacking combination therapies

Zealthy: Detailed Look

Zealthy

Doctor-overseen GLP-1 care offering a choice of compounded or brand-name medication

7/10
Good

Pros

  • Pick from compounded formulas or FDA-approved brand-name drugs
  • Buying three months at once cuts the per-month price sharply
  • Doctors oversee your care and stay involved throughout
  • Can arrange brand-name scripts for patients who carry insurance

Cons

  • A standalone $135/month membership fee pushes the total up
  • Its bundled tier ($297-449/mo) sits above a lot of rivals
Best For

People who want the flexibility to move between compounded and brand-name GLP-1s

How to Decide Between Them

There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:

You want the lowest monthly cost

Go with Zealthy at $151/month. Buying semaglutide in a 3-month batch brings it to $151/mo; bundled plans land at $297-449/mo.

You want the highest-rated program

Enhance MD has the edge with a 8.3 rating.

You want comprehensive medical support

Compare their support: Enhance MD offers board-certified doctors, while Zealthy provides licensed physicians who provide continued clinical support.

You are willing to invest more for premium care

Enhance MD at $249/month may offer features that justify the premium.

Enhance MD

Starting at $249/mo · Good

Visit Enhance MD

Zealthy

Starting at $151/mo · Good

Visit Zealthy

Frequently Asked Questions

Is Enhance MD better than Zealthy?

Enhance MD has a 8.3 rating while Zealthy has a 7 rating. The better choice depends on your priorities — Enhance MD is best for cost-minded patients curious about stacking combination therapies, while Zealthy is best for people who want the flexibility to move between compounded and brand-name glp-1s.

How much does Enhance MD cost compared to Zealthy?

Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%), while Zealthy starts at $151/month (buying semaglutide in a 3-month batch brings it to $151/mo; bundled plans land at $297-449/mo).

Do Enhance MD and Zealthy accept insurance?

Enhance MD does not accept insurance. Zealthy does not accept insurance.

Which GLP-1 medications does Enhance MD offer vs Zealthy?

Enhance MD offers Semaglutide, Tirzepatide, NAD+. Zealthy offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound.

Can I cancel Enhance MD or Zealthy at any time?

Enhance MD allows cancel anytime. Zealthy also allows cancel anytime.

Are Enhance MD and Zealthy available in my state?

Enhance MD is available in all 50 states. Zealthy is available in all 50 states.

Not sure Enhance MD or Zealthy is right for you?

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