Enhance MD vs TrimRx: Which GLP-1 Program Is Better? (2026)
We put Enhance MD and TrimRx head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend TrimRx
Between these two providers, TrimRx is our pick for most users. It offers a higher overall rating (9.3 vs 8.3), more affordable pricing. That said, Enhance MD may be the better fit if you are looking for cost-minded patients curious about stacking combination therapies.
TrimRx scores 9.3/10 in our independent evaluation at $179/month, while Enhance MD scores 8.3/10 at $249/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | TrimRx |
|---|---|---|
| Monthly Price | $249 | $179 |
| Rating | 8.3 / 10 | 9.3 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 45 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified doctors | Licensed doctors, individualized consultations, and unlimited check-ins |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Enhance MD: Detailed Look
Enhance MD
Doctor-directed weight management that also offers NAD+ add-ons
Pros
- Wallet-friendly way in, with pricing that begins at $115/month
- An uncommon NAD+ therapy choice to pair with your GLP-1
- Every protocol is overseen by board-certified doctors
Cons
- Claims that NAD+ aids weight loss aren't well supported by trials
- It's hazy about which drugs are compounded versus brand-name
Cost-minded patients curious about stacking combination therapies
TrimRx: Detailed Look
TrimRx
One-on-one GLP-1 consultations, prescriptions matched to you, and steady doctor support
Pros
- Doctor consultations shaped around your personal health history
- One bundled price with no buried fees or unexpected bills
- Free shipping and as many medical check-ins as you need
- Contract-free, so you can pause or stop treatment whenever
Cons
- Dispenses compounded formulas only, with no brand drugs
- Offered in a limited set of states rather than all 50
Anyone seeking individualized doctor consultations with clear, all-in pricing
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with TrimRx at $179/month. Semaglutide starts at $199/mo and tirzepatide at $299/mo, all bundled into one price..
TrimRx has the edge with a 9.3 rating.
TrimRx focuses on compounded medications at a lower price point.
Compare their support: Enhance MD offers board-certified doctors, while TrimRx provides licensed doctors, individualized consultations, and unlimited check-ins.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than TrimRx?
Enhance MD has a 8.3 rating while TrimRx has a 9.3 rating. The better choice depends on your priorities — Enhance MD is best for cost-minded patients curious about stacking combination therapies, while TrimRx is best for anyone seeking individualized doctor consultations with clear, all-in pricing.
How much does Enhance MD cost compared to TrimRx?
Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%), while TrimRx starts at $179/month (semaglutide starts at $199/mo and tirzepatide at $299/mo, all bundled into one price.).
Do Enhance MD and TrimRx accept insurance?
Enhance MD does not accept insurance. TrimRx does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs TrimRx?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. TrimRx offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel Enhance MD or TrimRx at any time?
Enhance MD allows cancel anytime. TrimRx also allows cancel anytime.
Are Enhance MD and TrimRx available in my state?
Enhance MD is available in all 50 states. TrimRx is available in 45 states.
Not sure Enhance MD or TrimRx is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.