Enhance MD vs Sesame Care: Which GLP-1 Program Is Better? (2026)
We put Enhance MD and Sesame Care head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 7.2). That said, Sesame Care may be the better fit if you are looking for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Sesame Care scores 7.2/10 at $225/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | Sesame Care |
|---|---|---|
| Monthly Price | $249 | $225 |
| Rating | 8.3 / 10 | 7.2 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified doctors | Licensed physicians booked one visit at a time |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Enhance MD: Detailed Look
Enhance MD
Doctor-directed weight management that also offers NAD+ add-ons
Pros
- Wallet-friendly way in, with pricing that begins at $115/month
- An uncommon NAD+ therapy choice to pair with your GLP-1
- Every protocol is overseen by board-certified doctors
Cons
- Claims that NAD+ aids weight loss aren't well supported by trials
- It's hazy about which drugs are compounded versus brand-name
Cost-minded patients curious about stacking combination therapies
Sesame Care: Detailed Look
Sesame Care
A low-cost telehealth marketplace that matches you with a doctor for as little as $25
Pros
- About the cheapest consult you'll find, with visits opening at $25
- Writes scripts for FDA-approved brand-name drugs
- Clear pay-per-visit pricing and nothing to subscribe to
- A broad bench of licensed physicians spanning all 50 states
Cons
- What the drug costs is billed on its own, apart from the visit fee
- No compounded route here — it's brand-name only, so the drug runs pricier
Insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Sesame Care at $225/month. Visits run $25-75, and the medication is billed separately at pharmacy rates ($200-1,400/mo). With insurance savings cards the total opens around $225/mo. The drug is not part of the visit fee..
Enhance MD has the edge with a 8.3 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: Enhance MD offers board-certified doctors, while Sesame Care provides licensed physicians booked one visit at a time.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than Sesame Care?
Enhance MD has a 8.3 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — Enhance MD is best for cost-minded patients curious about stacking combination therapies, while Sesame Care is best for insured patients chasing cheap doctor visits, keeping in mind the medication is billed separately.
How much does Enhance MD cost compared to Sesame Care?
Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%), while Sesame Care starts at $225/month (visits run $25-75, and the medication is billed separately at pharmacy rates ($200-1,400/mo). with insurance savings cards the total opens around $225/mo. the drug is not part of the visit fee.).
Do Enhance MD and Sesame Care accept insurance?
Enhance MD does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does Enhance MD offer vs Sesame Care?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel Enhance MD or Sesame Care at any time?
Enhance MD allows cancel anytime. Sesame Care also allows cancel anytime.
Are Enhance MD and Sesame Care available in my state?
Enhance MD is available in all 50 states. Sesame Care is available in all 50 states.
Not sure Enhance MD or Sesame Care is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.