Enhance MD vs Novi: Which GLP-1 Program Is Better? (2026)
We put Enhance MD and Novi head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 7.3), availability in all 50 states. That said, Novi may be the better fit if you are looking for people who want glp-1 care they can leave anytime, backed by plenty of clinician support.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Novi scores 7.3/10 at $199/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | Novi |
|---|---|---|
| Monthly Price | $249 | $199 |
| Rating | 8.3 / 10 | 7.3 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | 45 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified doctors | Licensed physicians you can reach without limits, plus nutritionist-designed meal plans |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Enhance MD: Detailed Look
Enhance MD
Doctor-directed weight management that also offers NAD+ add-ons
Pros
- Wallet-friendly way in, with pricing that begins at $115/month
- An uncommon NAD+ therapy choice to pair with your GLP-1
- Every protocol is overseen by board-certified doctors
Cons
- Claims that NAD+ aids weight loss aren't well supported by trials
- It's hazy about which drugs are compounded versus brand-name
Cost-minded patients curious about stacking combination therapies
Novi: Detailed Look
Novi
Commitment-free GLP-1 care that pairs $199/mo pricing with as much clinician time as you need
Pros
- Clear bundled pricing where nothing extra gets tacked on later
- Reach a clinician as often as you like for check-ins and dose tweaks
- Pay month by month, free of contracts or any minimum stay
- Comes with meal plans put together by a nutritionist plus an online community
Cons
- Once your prescription ships, that order can't be refunded
- A fairly young service that hasn't built up a long history yet
People who want GLP-1 care they can leave anytime, backed by plenty of clinician support
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Novi at $199/month. Opens at $199 for the first month, with nothing locking you into a contract.
Enhance MD has the edge with a 8.3 rating.
Compare their support: Enhance MD offers board-certified doctors, while Novi provides licensed physicians you can reach without limits, plus nutritionist-designed meal plans.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than Novi?
Enhance MD has a 8.3 rating while Novi has a 7.3 rating. The better choice depends on your priorities — Enhance MD is best for cost-minded patients curious about stacking combination therapies, while Novi is best for people who want glp-1 care they can leave anytime, backed by plenty of clinician support.
How much does Enhance MD cost compared to Novi?
Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%), while Novi starts at $199/month (opens at $199 for the first month, with nothing locking you into a contract).
Do Enhance MD and Novi accept insurance?
Enhance MD does not accept insurance. Novi does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs Novi?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. Novi offers Compounded Semaglutide, Brand-name GLP-1s.
Can I cancel Enhance MD or Novi at any time?
Enhance MD allows cancel anytime. Novi also allows cancel anytime.
Are Enhance MD and Novi available in my state?
Enhance MD is available in all 50 states. Novi is available in 45 states.
Not sure Enhance MD or Novi is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.