Enhance MD vs MyStart Health: Which GLP-1 Program Is Better? (2026)
We put Enhance MD and MyStart Health head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend MyStart Health
Between these two providers, MyStart Health is our pick for most users. It offers a higher overall rating (8.5 vs 8.3), more affordable pricing. That said, Enhance MD may be the better fit if you are looking for cost-minded patients curious about stacking combination therapies.
MyStart Health scores 8.5/10 in our independent evaluation at $224/month, while Enhance MD scores 8.3/10 at $249/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | MyStart Health |
|---|---|---|
| Monthly Price | $249 | $224 |
| Rating | 8.3 / 10 | 8.5 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified doctors | U.S.-licensed doctors you can reach without any cap on clinician visits |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Enhance MD: Detailed Look
Enhance MD
Doctor-directed weight management that also offers NAD+ add-ons
Pros
- Wallet-friendly way in, with pricing that begins at $115/month
- An uncommon NAD+ therapy choice to pair with your GLP-1
- Every protocol is overseen by board-certified doctors
Cons
- Claims that NAD+ aids weight loss aren't well supported by trials
- It's hazy about which drugs are compounded versus brand-name
Cost-minded patients curious about stacking combination therapies
MyStart Health: Detailed Look
MyStart Health
GLP-1 plans backed by a locked-in price and a results-or-refund pledge
Pros
- A locked rate means stepping up your dose never bumps the price
- Drop 10% of your body weight inside four months or get your money back
- One bundled price folds in free shipping and lab work
- Reaches all 50 states and turns consultations around within a day
Cons
- A handful of customers mention delays getting orders shipped out
- Switching to tirzepatide costs a lot more at $429 a month
People who value a money-back results pledge alongside a frozen price
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with MyStart Health at $224/month. Normally $299/mo; code SELFLOVE25 trims 25% off to $224/mo. Meds, labs, shipping, and unlimited clinician access all included.
MyStart Health has the edge with a 8.5 rating.
Compare their support: Enhance MD offers board-certified doctors, while MyStart Health provides u.s.-licensed doctors you can reach without any cap on clinician visits.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than MyStart Health?
Enhance MD has a 8.3 rating while MyStart Health has a 8.5 rating. The better choice depends on your priorities — Enhance MD is best for cost-minded patients curious about stacking combination therapies, while MyStart Health is best for people who value a money-back results pledge alongside a frozen price.
How much does Enhance MD cost compared to MyStart Health?
Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%), while MyStart Health starts at $224/month (normally $299/mo; code selflove25 trims 25% off to $224/mo. meds, labs, shipping, and unlimited clinician access all included).
Do Enhance MD and MyStart Health accept insurance?
Enhance MD does not accept insurance. MyStart Health does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs MyStart Health?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy.
Can I cancel Enhance MD or MyStart Health at any time?
Enhance MD allows cancel anytime. MyStart Health also allows cancel anytime.
Are Enhance MD and MyStart Health available in my state?
Enhance MD is available in all 50 states. MyStart Health is available in all 50 states.
Not sure Enhance MD or MyStart Health is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.