Enhance MD vs Hone Health: Which GLP-1 Program Is Better? (2026)
We put Enhance MD and Hone Health head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 6.3), availability in all 50 states, both brand-name and compounded medication options. That said, Hone Health may be the better fit if you are looking for people wanting one platform that handles weight loss alongside hormones and labs.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Hone Health scores 6.3/10 at $160/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | Hone Health |
|---|---|---|
| Monthly Price | $249 | $160 |
| Rating | 8.3 / 10 | 6.3 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 44 states |
| Consultation Fee | Included | $65 initial lab kit |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified doctors | Licensed doctors who pair lab testing with continued monitoring |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Enhance MD: Detailed Look
Enhance MD
Doctor-directed weight management that also offers NAD+ add-ons
Pros
- Wallet-friendly way in, with pricing that begins at $115/month
- An uncommon NAD+ therapy choice to pair with your GLP-1
- Every protocol is overseen by board-certified doctors
Cons
- Claims that NAD+ aids weight loss aren't well supported by trials
- It's hazy about which drugs are compounded versus brand-name
Cost-minded patients curious about stacking combination therapies
Hone Health: Detailed Look
Hone Health
Soup-to-nuts telehealth spanning GLP-1s, hormone therapy, and bloodwork
Pros
- One platform handling weight loss, hormones, longevity, and lab work
- In-depth diagnostics come baked in to steer your treatment
- Confidential video visits run by licensed doctors
- Your prescriptions arrive shipped straight to your address
Cons
- There's a standalone membership charge ($25-149/mo) layered over the meds
- Semaglutide isn't stocked — your choices are liraglutide or tirzepatide
People wanting one platform that handles weight loss alongside hormones and labs
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Hone Health at $160/month. Liraglutide at $160/mo, tirzepatide $349-499/mo, plus a membership fee on top.
Enhance MD has the edge with a 8.3 rating.
Hone Health focuses on compounded medications at a lower price point.
Compare their support: Enhance MD offers board-certified doctors, while Hone Health provides licensed doctors who pair lab testing with continued monitoring.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than Hone Health?
Enhance MD has a 8.3 rating while Hone Health has a 6.3 rating. The better choice depends on your priorities — Enhance MD is best for cost-minded patients curious about stacking combination therapies, while Hone Health is best for people wanting one platform that handles weight loss alongside hormones and labs.
How much does Enhance MD cost compared to Hone Health?
Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%), while Hone Health starts at $160/month (liraglutide at $160/mo, tirzepatide $349-499/mo, plus a membership fee on top).
Do Enhance MD and Hone Health accept insurance?
Enhance MD does not accept insurance. Hone Health does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs Hone Health?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. Hone Health offers Compounded Liraglutide, Compounded Tirzepatide.
Can I cancel Enhance MD or Hone Health at any time?
Enhance MD allows cancel anytime. Hone Health also allows cancel anytime.
Are Enhance MD and Hone Health available in my state?
Enhance MD is available in all 50 states. Hone Health is available in 44 states.
Not sure Enhance MD or Hone Health is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.