Enhance MD vs Fridays: Which GLP-1 Program Is Better? (2026)
We put Enhance MD and Fridays head-to-head — what you actually pay each month, which GLP-1 medications you can get, the level of clinician support, and where each one wins — so you can pick the cheaper, better-fit weight loss program in minutes.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 6.8), availability in all 50 states. That said, Fridays may be the better fit if you are looking for people after an all-in-one program with coaching, diet help, and pricing they can flex.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Fridays scores 6.8/10 at $249/month. Both programs connect you with a licensed physician and deliver medication straight to your door. Each score weighs five things: safety and medical oversight (30%), pricing transparency (25%), value for money (20%), quality of clinical support (15%), and how fast you can get started (10%). We build these comparisons ourselves — no provider buys a better rating or a higher spot. Pricing checked April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | Fridays |
|---|---|---|
| Monthly Price | $249 | $249 |
| Rating | 8.3 / 10 | 6.8 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | 49 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified doctors | Licensed clinicians backed by health coaches and dietary guidance |
Figures show entry-level cash prices before any insurance. What you ultimately pay can change with your plan and the specific medication. Last checked April 2026.
Enhance MD: Detailed Look
Enhance MD
Doctor-directed weight management that also offers NAD+ add-ons
Pros
- Wallet-friendly way in, with pricing that begins at $115/month
- An uncommon NAD+ therapy choice to pair with your GLP-1
- Every protocol is overseen by board-certified doctors
Cons
- Claims that NAD+ aids weight loss aren't well supported by trials
- It's hazy about which drugs are compounded versus brand-name
Cost-minded patients curious about stacking combination therapies
Fridays: Detailed Look
Fridays
Whole-person GLP-1 weight loss pairing meds with coaching and dietitian guidance
Pros
- Every plan bundles clinician visits, coaching, and dietary guidance together
- Going annual pulls the monthly cost down toward the $150 mark
- Brand-name prescriptions can be run through your insurance
- Use HSA or FSA dollars as long as you keep the itemized receipt
Cons
- Louisiana residents are out of luck — coverage stops at 49 states
- The deepest discount only applies if you pay the year up front
People after an all-in-one program with coaching, diet help, and pricing they can flex
How to Decide Between Them
There is no single winner for everyone — it comes down to what matters most to you. Match your priority to the scenarios below to see which provider fits:
Go with Enhance MD at $249/month. Semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%.
Enhance MD has the edge with a 8.3 rating.
Fridays accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: Enhance MD offers board-certified doctors, while Fridays provides licensed clinicians backed by health coaches and dietary guidance.
Frequently Asked Questions
Is Enhance MD better than Fridays?
Enhance MD has a 8.3 rating while Fridays has a 6.8 rating. The better choice depends on your priorities — Enhance MD is best for cost-minded patients curious about stacking combination therapies, while Fridays is best for people after an all-in-one program with coaching, diet help, and pricing they can flex.
How much does Enhance MD cost compared to Fridays?
Enhance MD starts at $249/month (semaglutide runs $249/mo and tirzepatide $379/mo, with yearly plans trimming roughly 15%), while Fridays starts at $249/month (drops to as little as $150/mo when you commit to a full year).
Do Enhance MD and Fridays accept insurance?
Enhance MD does not accept insurance. Fridays accepts insurance.
Which GLP-1 medications does Enhance MD offer vs Fridays?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. Fridays offers Compounded Semaglutide, Compounded Tirzepatide, Brand-name GLP-1s (with insurance).
Can I cancel Enhance MD or Fridays at any time?
Enhance MD allows cancel anytime. Fridays also allows cancel anytime.
Are Enhance MD and Fridays available in my state?
Enhance MD is available in all 50 states. Fridays is available in 49 states.
Not sure Enhance MD or Fridays is right for you?
Take our 6-question quiz and we'll point you to the program that fits your budget and goals best.